In spite of the fact that many consider cardarine (GW 501516) to be a SARM, it is technically a PPAR-delta agonist (peroxisome proliferator-activated receptors). In fact, it is usually sold as a SARM, just like a tomato being a fruit is always sold as a vegetable. Cardarine was developed for health benefits, and it works by activating the same pathways that the body activates when we exercise. In this article we will discuss everything you need to know about this potent drug in plain English.
Cardarine is used by athletes competing in many different sports. For instance, endurance athletes may increase exercise endurance by stacking this PPAR with the AMP analog drug AICAR, or run cardarine solo. As a result, they will have a greater ability to reach higher RPM’s during their runs without hitting the maximum heart rate. This will allow the runner/cyclist/swimmer to cheat their maximum heart rates and go longer without getting winded, making this stack an incredible weapon to use in endurance sports. Actually, from personal experience I can tell that cardarine can knock over 30-45 seconds off a 5K time if used leading up to a race.
Regarding the bodybuilders, cardarine can benefit them in two ways:
1. Its ability to burn fat
2. Its ability to help the athlete have harder and longer workouts, without getting winded.
When a lifter does a set, their heart rate will skyrocket, and many times the athlete will reach failure slower when on cardarine because they can get in that extra rep or two. Furthermore, you will need less rest periods in between sets, and bodybuilders who like to do cardio after their weight training will enjoy these benefits as well.
Cardarine was heavily abused by numerous athletes ahead of the 2008 Beijing Olympic Games and was banned by WADA in 2009, which categorized it as a ‘hormone and metabolic modulator.’
Moreover, numerous cyclists have been busted for using cardarine; Russian cyclist Valery Kaykov was suspended, and in 2013 Miguel Ubeto from Venezuela was kicked off the Lampre team. In fact, last year, Elena Lashmanova of Russia, the world record holder in the 20M race walk, tested positive for cardarine.
In terms of obesity, cardarine reverses metabolic abnormalities in obese and pre-diabetic men by stimulating fatty acid oxidation. That is, it burns fat by increasing glucose uptake in skeletal muscle tissue, which changes the body’s metabolism to burn fat for energy instead of muscle or carbs. Incredibly, it does all this without dropping blood sugar levels like diabetic drugs do. Interestingly, when mice were given a high fat diet, they still lost fat, which proves that cardarine prevents obesity.