• Rad 140 10mg

Radirol SARM (Selective Androgen Receptor Modulator). Investigational name: RAD-140

Radirol profile:

Radirol (RAD-140 or RAD 140) is a potent, orally bioavailable and nonsteroidal selective androgen receptor modulator (SARM).1

RAD140 is efficacy and potency selective. style="cursor: pointer; outline: none medium;">1 It exhibits a fully anabolic effect on muscle with reduced efficacy on the prostate and seminal vesicles." style="cursor: pointer; outline: none medium;">2 RAD140 can also stimulate muscle weight increase at lower dose than that required to stimulate prostate weight increase in vivo. style="cursor: pointer; outline: none medium;">1RAD140 can moderately antagonise seminal vesicle stimulation induced by testosterone. style="cursor: pointer; outline: none medium;">2RAD140 has excellent pharmacokinetics and has been shown to be a potent anabolic in nonhuman primates.1

Although RAD 140 can induce dramatic increase in body weight over a short time it does not promote elevation of liver enzyme transaminase levels even at a dose 10-fold greater than the fully effective dose. Clinical chemistry had also showed RAD 140 lipid (LDL, HDL and triglycerides) lowering effects.1,2

RAD-140 (2-chloro-4-{[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino}-3-methylbenzonitrile) (also known as RAD-140, RAD140) is an investigational selective androgen receptor modulator (SARM) under development by Radius Health, Inc. for potential therapeutic benefit of conditions such as muscle wasting and breast cancer.2 It has a very good preclinical profile, having completed preclinical toxicology in both rats and monkeys. RAD140 has been also prepared for phase I clinical studies as a potential treatment of severe weight loss due to cancer cachexia.

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Rad 140 10mg

  • Product Code: Pro Pharma
  • Availability: In Stock
  • €72.00

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