• Susten 250

Susten 250 (Sustanon - 250)


1 ml:

Testosterone propionate 30 mg

Testosterone phenylpropionate 60 mg

testosterone isoxapronate 60 mg

Testosterone decanoate 100 mg

The total testosterone content is 176 mg / ml.



1 ml - ampules of colorless glass (1) - packages of cardboard.

Description:

Pharmacological action

Testosterone is a major endogenous hormone essential for normal growth and development of male genital organs and male secondary sexual characteristics. During life in adult males, testosterone is indispensable for the functioning of the testicles and adjacent structures, as well as for the maintenance of libido, good health, erectile potency, and for the function of the prostate and seminal vesicles.


The treatment of hypogonadal men with the drug leads to a clinically significant increase in the concentrations of testosterone, dihydrotestosterone, estradiol and androstenedione in plasma, as well as to the decrease in the level of GSPG (globulin binding to sex hormones); levels of luteinizing hormone (LT) and follicle stimulating hormone (FSH) are restored to normal values.


Treatment with the drug leads to a decrease in the symptoms of testosterone deficiency. In addition, the mineral density of bones and muscle mass increases, and in fat patients there is a decrease in body weight. In the course of treatment, sexual functions, including erectile function and libido, are normalized. With the use of the drug, concentrations of HDL (high-density lipoprotein), LDL (low-density lipoprotein) and triglycerides decrease in blood serum, hemoglobin and hematocrit concentrations increase, with no clinically relevant changes in the level of hepatic enzymes and PSA (prostatic specific antigen). The drug can cause an increase in the size of the prostate gland, while functional changes are not noted. In hypogonadal men suffering from diabetes, the use of androgens improves insulin sensitivity and / or reduces glucose concentration in plasma.


In boys with growth retardation and puberty, the use of androgens accelerates growth, stimulates the development of secondary sexual characteristics.


Indications

- testosterone substitution therapy in men in pathological conditions associated with primary and secondary hypogonadism, both congenital and acquired.


Dosing mode

The drug  should be administered deeply in / m.

Dosage regimen, as a rule, depends on the patient's individual response to treatment.


Contraindications

- Established or suspected prostate or thoracic carcinoma;


- increased sensitivity to any component of the drug;


- Children under 3 years of age (due to the content of the drug in the form of benzyl alcohol).


With caution: boys in the prepubertal period to avoid premature closure of epiphyses and premature puberty; chronic heart failure, renal and / or hepatic insufficiency to avoid swelling; diabetes mellitus; hypertrophy of the prostate with symptoms of urinary retention; sleep apnea, and also risk factors such as obesity and chronic pulmonary disease; childhood


Pregnancy and lactation

This drug is contraindicated during pregnancy.

There is not enough data on the use of this drug during breast-feeding.

Application for violations of the liver function

Take caution to take the drug with violations of the liver function, with hepatic insufficiency.


Application in case of abnormal kidney function

With caution, take medication for impaired renal function, with renal failure.


Application for children

It is contraindicated to prescribe this drug to children under 3 years of age.

Use caution with this product in children older than 3 years of age.

With caution: boys in the prepubertal period to avoid premature closure of epiphyses and premature puberty;


Special instructions

Medical supervision should be performed on patients receiving Susten 250 before treatment and on a quarterly basis for 12 months and subsequently once a year.


The following studies are to be conducted:

- A finger rectal study (PI) to exclude benign prostatic hyperplasia (see the same sentence) and the determination of a specific prostatic antigen (PSA) to exclude subclinical forms of prostate cancer.

- measurement of hematocrit and hemoglobin to exclude polycythemia.

Patients with pre-existing cardiac, renal or liver disease, androgen treatment may cause complications characterized by edema with or without acute heart failure.


In the event of unwanted reactions associated with the use of androgens, the treatment with Susten 250 should be temporarily interrupted and, after the disappearance of symptoms, resume at a lower dose.


The use of androgens is not for the purpose, but to increase endurance athletes, presents serious health risks. The use of androgens, including Susten 250, in elderly patients, increases the likelihood of hypertrophy or prostate cancer.


Influence on the ability to drive vehicles and control mechanisms


To date, there has been no reported influence on the concentration of attention and the speed of psychomotor reactions when using the drug Susten-250.


Overdose

The acute toxicity of the drug Sustanon-250 when administered intravenously is very low. Priapism in men is a symptom of chronic overdose. In the case of the development of priapism treatment with Susten-250 should be temporarily stopped, and after the disappearance of the indicated symptom to resume in lower doses.


Drug interaction

Drugs inducing or inhibiting enzymes can lower or increase testosterone concentrations accordingly. Therefore, the dose and / or intervals between injections may need to be corrected.

Androgens can increase glucose tolerance and reduce the need for insulin or other hypoglycemic drugs in diabetic patients.

High doses of androgens can enhance the effect of coumarin-type anticoagulants, which reduces the dose of these drugs.


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Susten 250

  • Product Code: B.M. Pharmaceuticals
  • Availability: In Stock
  • 58.00€
  • 45.00€


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Tags: Susten 250, Testosterone